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SHINTAX ®
Shintax is Cefotaxime sodium, parenteral third
generation cepholosporin and has a bactericidal effect with broad spectrum
MODE OF ACTION
Shintax inhibits the third and final round of
bacterial cell wall synthesis by preferentially binding to the specific
penicillin-binding proteins (PBP) located in the cell wall which in turn
causes the death of the bacteria.
INDICATIONS
Prophylaxis & treatment of most of the surgical
infections. In gyne & obs for use in pre- and post-partal infections
as well as in all gyne Infections. In RTI, Meningitis, Septicemia,
Pneumonia, TUI, SSTI, Intra-abdominal infections &
peritonitis.
DOSAGE
Recommended dose is 1gm im or iv every 12 hourly. In
severe infections 3-6 gram in 3-4 divided doses up to 12 gram daily. In
children and neonates 50-100mg/kg in 3-4 divided doses.
CONTRAINDICATION
Hypersensitivity to Cephalosporin and penicillin
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